Bioidentical Pellets: Long-Acting Hormone Therapy

Pellets are micro-implants containing bioidentical hormones, inserted under the skin, that release the active substance steadily over 3 to 6 months. The method has been used worldwide for about half a century and is especially common in the Western hemisphere.

Medical editor: Vitalia Kurach · Reviewed by a doctor · Updated: 09.08.2026

What "bioidentical" means

Bioidentical hormones are molecularly identical to those the body itself produces — unlike a number of synthetic analogues. As a result, their action is more physiological, and steady release from the pellet avoids the concentration "swings" typical of pills and gels.

Who the therapy is for

• women — for symptoms of menopause and perimenopause: hot flashes, sleep disturbances, decreased libido, mucosal dryness, mood swings;
• men — for age-related testosterone decline: reduced energy, libido, muscle mass;
• patients on anti-aging programs — as part of managing hormonal balance.
• Therapy is only decided based on hormonal testing.

How insertion works

Pellet insertion is a short outpatient procedure under local anesthesia: through a tiny incision, the implant is placed under the skin (typically in the buttock or abdomen). The visit takes 45 minutes; no stitches are needed. This is followed by ongoing lab monitoring of hormone levels. Combined with the clinic's other technologies, this method delivers years of comfortable living without "pharmacy dependence."

Pellet therapy prices

Questions & Answers

Author: PERFECT IMPERIAL Private Medical Institute editorial team.

Medical editor: Vitalia Kurach — dermatovenereologist, sexopathologist, andrologist, dermatosurgeon; specialist in intimate contouring and regenerative medicine; Medical Director of the Institute.

Published: 09.08.2026 · Updated: 09.08.2026

This material is for informational purposes only and does not replace a doctor's consultation. Contraindications exist — a specialist consultation is required. Expected results are described based on the clinic's experience; individual results depend on the patient's baseline condition and adherence to recommendations.